Port Sarim is by Falador. It has a few shops including a jewelery shop, an axe store, a fishing shop a bar, a rune shop, and a food shop. There is also a jail, in which the goblin "Wormbrain" is in. He has a map piece needed for the "Dragon Slayer" quest(http://runescape.neoseeker.com/wiki/Dragon_Slayer). You can also buy passage to the island of "Karmaja" by talking to someone at the docks. There are more than one person that you can buy a trip to Karmaja from, but they are all on the docks. There is also a range within a house that you can use to cook on.
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